NUKLEONIKA 2005, 50(4):139-141

A CONVENIENT METHOD FOR SYNTHESIS OF 11-[14C]-LOXAPINE

Nader Saemian, Gholamhossein Shirvani, Hojatollah Matloubi

Chemical Division, Nuclear Research Center, AEOI, P. O. Box 11365-3486, Tehran, Iran

8-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepine labeled with carbon-14 in 11-position has been synthesized as part of a 5-step sequence from potassium [14C] cyanide.