Factors affecting the coordination number of central metal ions in chelate complexes, and hydration of metal chelates have been investigated. Novel complexes of technetium and rhenium are being studied as potential radiopharmaceuticals or as their precursors. Also novel transition metal complexes of expected antitumor properties are being synthesised and studied.
Isotope effects in chemical reactions are studied, in particular, the influence of coordinative environment of the central metal ion on the properties of its isotopes. Special attention is focused upon the use of the nuclear field effect for the developing of new effective methods for separation of stable isotopes.
